EVIDENCE OF COPPER NANOPARTICLES AND POLY I:C MODULATING CAS9 INTERACTION AND CLEAVAGE OF COR (CONSERVED OMICRON RNA)

Evidence of Copper Nanoparticles and Poly I:C Modulating Cas9 Interaction and Cleavage of COR (Conserved Omicron RNA)

Conserved omicron RNA (COR) is a 40 base long 99.9% conserved sequence in SARS-CoV-2 Omicron variant, predicted to form a stable stem loop, the targeted cleavage of which can be an ideal next step in controlling the spread of variants.The Cas9 enzyme has been Baker traditionally utilized for gene editing and DNA cleavage.Previously Cas9 has been sh

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In vitro assessment of the anthelmintic activity of copper oxide and zinc oxide nanoparticles on egg and adult stages of Fasciola hepatica: evidence on oxidative stress biomarkers, and DNA damage

Abstract Objectives Fasciolosis is of significant economic and public health importance worldwide.The lack of a successful vaccine and emerging resistance in flukes to the drug of choice, triclabendazole, has initiated the search for alternative approaches.In recent years, metallic nanoparticles have been extensively investigated for their anthelmi

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THE POSITIONING OF THE DECISION-MAKING FACTOR FROM THE AGRO-FOOD COMPANIES IN CLUJ COUNTY TOWARDS THE INTERNAL AND EXTERNAL AUDIT

The audit process is valuable for the company because of its benefits mainly because of the professional opinion expresses by the auditor and also the recommendations useful to the company.The main purpose of this article is to highlight the attitude of the decision-making factor Wine Tumbler Couple Card from the agro-food companies from Cluj Count

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Heterologous production of the adhesin LIC13411 from pathogenic Leptospira facilitates binding of non-pathogenic Leptospira in vitro and in vivo

Leptospirosis is an important cause of morbidity and mortality worldwide.Disease severity ranges from asymptomatic colonization to widespread hemorrhage and multiorgan dysfunction.The causative agents, Leptospira spp., are zoonotic Gram-negative spirochetes.One important step in pathogenesis is binding of bacterial adhesins to host components.Previ

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